Prion Proteins

Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU.

Also Known As:

AltPrP; Alternative Prion Protein; CD230 Antigen; Creutzfeldt-Jakob Disease Protein; Fatal Familial Insomnia Protein; Major Prion Protein; Prion Protein; Antigen, CD230; Creutzfeldt Jakob Disease Protein; Prion Protein, Alternative; Prion Protein, Major; PrP Proteins

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - GPI-Linked Proteins: 145
        Prion Proteins: 5458
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - GPI-Linked Proteins: 145
        Prion Proteins: 5458
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - GPI-Linked Proteins: 145
        Prion Proteins: 5458
    - Lipid-Linked Proteins: 1
      - GPI-Linked Proteins: 145
        Prion Proteins: 5458
  - Prions: 4854
    - Prion Proteins: 5458

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Disease

Drug/Important Bio-Agent (IBA)